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The most recent rulemakings on these regulations were in the January 12, 2001 final rule (66 FR 3358 through 3374), and in the August 1, 2003, final rule (68 FR 45423 and 45434)

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The prevalence of obesity is increasing rapidly, and obesity also contributes to numerous health problems

Limitations The limitation of the study includes a limited sample size, the absence of a control group with no pharmacological treatment, placebo, or an alternative pharmacological regimen, and the absence of female patients in this case series