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The GSH/GSSG redox couple is considered the main cellular redox buffer and, as such, the concentration ratio between reduced and oxidized forms of the tripeptide ([GSH]/[GSSG] ratio) is often used as an indicator of the cellular redox state (Wu et al., 2004)

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Tabibzadeh S, Satyaswaroop PG, von Wolff M, Strowitzki T: Regulation of TNF-alpha mRNA expression in endometrial cells by TNF-alpha and by oestrogen withdrawal

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