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Upon further validation, the plasma exosomal CYP2E1 pathway may help to better understand ALC-, APAP-, and other xenobiotic-induced toxicity, especially in the extra-hepatic tissues

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Translate this page into: Reversible hyperpigmentation as the first manifestation of dietary vitamin B 12 deficiency 1 , Satish Chand 1 , Manish Bansal 2 , Kanchan Srivastava 1 , Sanjay Singh 1 1 Department of Dermatology and Venereology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, UP, India 2 Department of Dermatology, All India Institute of Medical Sciences, New Delhi, India Correspondence Address : Sanjay Singh C-9, New Medical Enclave, Banaras Hindu University, Varanasi - 221 005 India Sir, Vitamin B 12 deficiency is considered to be rare and presents with different combinations of neurological manifestations, hematological changes, discoloration of skin, hair and nails, weakness, syncope and diarrhea