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The overall discontinuation rate due to adverse events was approximately 10%, which compares favorably to most compounds in this class

The agency said such discrepancies raise concerns about the safety of the trial subjects and the reliability of the trial data.

Many men in their 30s, 40s, and 50s assume these changes are simply part of aging

In the Lancet 2021 Phase 2 trial at 4.5 mg/week, nausea occurred in 47% of participants, injection-site reactions in 43%, constipation in 21%, and vomiting in 8%

This allows it to act directly on the gastrointestinal liningwhere it naturally originates and exerts many of its effects