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Deferiprone (DFP), a commonly used iron chelating agent, demonstrates the ability to cross the blood-brain barrier (BBB) and transfer iron from DFP-Fe to TF for the treatment of serum iron overload

Additionally, the prevalence of OSAHS was markedly higher in postmenopausal females not undergoing hormone replacement therapy than in both premenopausal females and postmenopausal females receiving hormone replacement therapy, particularly when controlling for confounding variables such as body mass index (BMI) and neck circumference (5, 6)

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It acted via non-competitive inhibition, binding to non-active sites and inducing structural rearrangements, with reduced -helical content and increased -sheet and random coil, thereby disrupting ACE function without active-site competition