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10.1128/aem.02706-19 113 WillemsR

MYLK2 and MYLK3 are skeletal- and cardiac-specific MLCK-encoding genes, 153,154 respectively, while MYLK1 encodes long non-muscle isoforms (~210 kDa) including MLCK1 (full-length long MLCK) and MLCK2

doi:10.1006/bcmd.2002.0556

These essential processes help shape appropriate cellular responses at infection sites but are also responsible for dysregulated activation of systemic inflammation and are potentially harmful to the host