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Iron Dysregulation in Alzheimer's Disease: Multimodal Brain Permeable Iron Chelating Drugs, Possessing NeuroprotectiveNeurorescue and Amyloid Precursor ProteinProcessing Regulatory Activities as Therapeutic Agents. Progress in Neurobiology 82: 348360

[PMC free article: PMC3144781] [PubMed: 21730304] 185

One such adaptation she and her colleagues have been studying is an increase in the amount of the enzyme glutamine synthetase, which makes glutamine from other starting materials, namely glucose

When the vasculature that feeds it is compromised by inflammation and endothelial damage which chronically elevated homocysteine promotes cognitive performance suffers