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With its two activating groups, the benzene ring is highly reactive towards electrophilic aromatic substitution

The treatment is 50,000 IUs of Vitamin D3 given monthly, and all other supplementation for vitamin D should be discontinued for the month following injection

Enos RT, Velzquez KT, McClellan JL, Cranford TL, Nagarkatti M, Nagarkatti PS, Davis JM, Murphy EA

Supplemental In Vitro Models In vitro models, including human cells and tissues, may provide additional insights into a drugs potential effects on humans

In contrast, 25HC, but not lanosterol binds and induces conformational change of SCAP to inhibit SERBP processing 31,32