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evaluated the diagnostic accuracy of specific GGT fractional enzymatic activity patterns in pleural malignant mesothelioma in blood samples of 175 workers at risk (i.e., previously exposed to asbestos), 157 (non-exposed) healthy subjects, and 37 patients with pleural malignant mesothelioma by using a molecular exclusion chromatographic method [29]

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Treatment with Reclast resulted in a 6.7% increase in BMD at the lumbar spine, 6.0% at the total hip, and 5.1% at the femoral neck, over 3 years as compared to placebo

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In some cases, such as certain oncology programs where the compound's risk profile makes it unsuitable for healthy subjects, patients may participate instead