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The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin

Arsenical thiols may also form (Fricke et al

The main test consists of a single ordered dose progression in which animals are dosed, one at a time, at a minimum of 24-hour intervals

Store at 2C to 8C after reconstitution

This finding moves beyond isolated case reports and is corroborated by large cohort studies documenting an increased incidence of severe infections with rituximab use 35