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For candidate drugs Jingfang Granules that have not been thoroughly explored in the field of OA, standardized OA mouse models should be used for rigorous pharmacodynamic validation

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*Correspondence: Hua-you Luo, [email protected] Zhu, [email protected] Xu, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

These findings underscore the importance of mitochondrial health in disc homeostasis and provide novel insights into precise strategies for treating age-related degenerative spinal diseases