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2.2 Clinical diagnosis To date, there is a lack of established diagnostic standards for BIPN, which leads to a frequent underestimation due to patient underreporting and insufficient assessment by physicians (Park et al., 2019)

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PLoS One 7 , e41281 (2012)

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Sharief MK, Hentges R (1991) Association between tumor Necrosis factor- and disease progression in patients with multiple sclerosis

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Conclusion: Patients with chronic liver disease were more likely to meet criteria for d-CCM

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In 24 hpi trophozoite-stage parasites, hemoglobin and heme levels were not measurably different, but hemozoin levels were significantly decreased in resistant parasites compared to sensitive parasites (Fig 2B), indicative of decreased turnover of heme into hemozoin in resistant parasites over the preceding 24 h of the parasite lifecycle

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