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Nikolaeva S, Ansermet C, Centeno G, Pradervand S, Bize V, Mordasini D, Henry H, Koesters R, Maillard M, Bonny O, Tokonami N, Firsov D (2016) Nephron-specific deletion of circadian clock gene bmal1 alters the plasma and renal metabolome and impairs drug disposition

In particular, our study showed that the intracellular depletion of GSH is able to induce cellular stress in NO-producing cells through a NO-dependent mechanism, such as inhibition of CcOX activity, DNA damage, and S-NO and 3-nitrotyrosine (NO 2 -Tyr) protein accumulation ( Figure 1 )

Jos A, Trujillo-Hernandez L, Bariat TA, Enders LC, Strader J-P, Reichheld, Christophe Belin (2020) A glutathione-dependent control of the indole butyric acid pathway supports Arabidopsis root system adaptation to phosphate deprivation

Moreover, the ROS activates the NF-kappaB transcriptional factor, which promotes the transcription of various genes, including those involved in the synthesis of nitric oxide and proinflammatory cytokines

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