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Research into diseases of nutritional deficiency was occurring at the height of the Pasteurian revolutionor germ theory of diseasea time when microscopic organisms were thought to be the cause of all maladies

Tamura et al., FEMS microbiology letters, 99:321, 1992) which affects what is termed the fluidity of the cell membrane as well as the contents of the cell interior (ethanol is a small molecule to which the membrane is partially permeable)

It is considered a multipurpose plant: ripe fruits are used in preserves, jellies and beverages (Reference Onilude, Kazeem and Adu14) , while leaves, roots, bark and seeds are used in herbal medicine for malaria, haemorrhages, gastrointestinal disorders, inflammation and metabolic syndrome regulation, among others (Reference Stephen-Onojedje, Ogheneovo Asagba and Kadiri15)

27 , 195209.e196 (2018)

Reversal of oxidative stress-induced anxiety by inhibition of phosphodiesterase-2 in mice