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One of the mutants, bzs285 , carried a mutation that creates a stop codon after amino acid 284, resulting in deletion of 52 amino acids at the C terminus of bzr1-1D protein (Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] 255.Cao Y, et al

In other words, it's when the thyroid is underactive. For many women, the root cause of hypothyroidism is Hashimoto's thyroiditis, an autoimmune condition where the body attacks its own thyroid tissue