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Twice subacute MPTP administrations induced time-dependent dopaminergic neurodegeneration and inflammation in midbrain and ileum, as well as gut microbiota disorders in PD mice

The renoprotective, regenerative, anti-apoptotic, antifibrotic, anti-inflammatory, mitochondrial hemostasis, and immunomodulatory effects of MSC-EVs have been reported in these studies [161] that are mediated by a variety of mechanisms [158]