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SP600125, a classical ATP-competitive inhibitor of JNK, has been reported to have protective effects against AIH in vivo and in vitro

2019;177:1888-1902.e21

Its widely assumed that a reasonable amount of ROS is essential for a variety of biological processes

Abstract This study investigated the therapeutic effects of Dapansutrile, a selective NLRP3 inflammasome inhibitor, on ovarian dysfunction in a dihydrotestosterone (DHT)-induced polycystic ovary syndrome (PCOS) rat model