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(4)KO group: TPH1 knockout mice were treated i.p with APAP (TPH1, the rate-limiting enzyme for the synthesis of peripheral serotonin)

This upregulation leads to an increased expression of lipogenic genes, including sterol regulatory element-binding proteins (SREBP1c) and diacylglycerol acyltransferase-2 (DGAT2), which suggests that miR-370 provides a further point of regulation of this pathway 86

Transfusional iron overload and intravenous iron infusions modify the mouse gut microbiota similarly to dietary iron

In EF-hand proteins, the open of the EF-hand structure exposes a hydrophobic surface, which binds the target sequence (Lewit-Bentley and Rety, 2000

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