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doi: 10.1016/S1473-3099(20)30796-9 29 Bastidas-CaldesC.de WaardJ

The polar residues involve in citalopram binding are HIS335, Q450, N590, Q377, T378, H382, N1208, T1241, and T1242

The ARIC investigators

Yun et al., 2018)

As such, fentanyl may act on peripheral structures, brain regions without a bloodbrain barrier, and brain structures within the blood brain barrier 15,20