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Oxidative stress in ALS: A mechanism of neurodegeneration and a therapeutic target

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Studies about HTS or DR in brain organoid models for neurodevelopmental diseases and mitochondrial disorders have not yet been reported, which to some extent reflects the enormous difficulty and limitations of brain organoids in modeling these groups of diseases and their applications in drug discovery

Carter BZ, Mak PY, Mak DH, Shi Y, Qiu Y, Kornblau S, McQueen T, Weng D, Burns J, Andreeff M

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