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Despite being derived from angiotensin IV (a true peptide), Dihexa's chemical structure has been extensively modified: it incorporates non-natural amino acid analogs and a hexanoic acid cap that make it structurally distinct from conventional peptides

The rationale is: First course: Addresses the existing senescent cell burden

The incorporation of carbon fluorinated moieties into the polymer backbone could allow for the codelivery of oxygen and therefore enable the treatment of hypoxic tumors

At the molecular level, it modulates the expression of over 4,000 human genes, roughly 6% of the genome, according to a 2012 Broad Institute Connectivity Map analysis published by Pickart, Campbell, and colleagues

Campos PMBGM, Franco RSB, Kakuda L, Cadioli GF, D Angelo Costa GM