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et al., Cell, 2022 2274-C ADIPOSE TISSUE NAT10 IS ESSENTIAL FOR THE DEVELOPMENT OF NAFLD Qianren Zhang 1 , Rui Xue 1 , Ren Tianyi 1 and Jiangao Fan 2 , (1)Department of Gastroenterology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, (2)Department of Gastroenterology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China Background: Adipose tissue dysfunction has been closely linked with nonalcoholic fatty liver disease (NAFLD), but the underlying mechanisms remain to be elucidated