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Lower urinary tract symptoms are a common non-motor symptom in individuals with PD and atypical parkinsonian disorders and are divided into disturbances of the storage phase, mostly due to bladder detrusor hyperactivity, and disturbances of the voiding phase due to detrusor-sphincter dyssynergia or hypocontractile detrusor [1, 88, 167]

Age, current medications, medical history, and even lifestyle factors can change how a treatment works

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start with lower doses and titrate gradually

This loop is the storage mechanism for B12 in normal mammals as the intrinsic factor from the stomach holds onto the B12 and saves it for the ilium to recover and send to the liver