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Blood 116 , 25822589 (2010)

(c) Establishing the Performance Threshold for the CY 2025 Performance Period/2027 MIPS Payment Year Using the mean of 75 points from the CY 2017 performance period/2019 MIPS payment year continues to be the most appropriate option for establishing the performance threshold for the CY 2025 performance period/2027 MIPS payment year for various reasons described in this section, including: providing consistency for MIPS eligible clinicians while allowing additional time for more recent data to become available, continuing to provide opportunities for MIPS eligible clinicians to gain experience with cost measure scoring (particularly the methodology we are finalizing in section IV.A.4.f.(1)(d)(ii)(B) of this final rule), and ensuring that we do not inadvertently disadvantage certain clinician types, such as small practices and solo practitioners, as we increase the performance threshold

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Role of endoplasmic reticulum stress in the anticancer activity of natural compounds