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Safety, tolerability, and pharmacokinetics of PL 14736, a novel agent for treatment of ulcerative colitis, in healthy male volunteers

and Song, B-J

doi: 10.1101/gad.271130.115 17 CheungE

It can potentially alleviate symptoms of depression and anxiety, leading to improved overall mental health

For example, the role of macrophages in inflammation has moved away from the dichotomy of pro-inflammatory M1 and anti-inflammatory M2 cells, being replaced by a more nuanced view, encompassing a diversity of heterogeneous macrophage sub-types, likely with specialized functions [36]