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Renal dosing adjustments for adult patients (18 years and older) with cIAI and cUTI with CrCl 50 mL/min or less a,b a,b 30 to 50 CrCl (mL/min) 750 mg (500 mg and 250 mg) intravenously every 8 hours 15 to 29 CrCl (mL/min) 375 mg (250 mg and 125 mg) intravenously every 8 hours For patients with end-stage renal disease (ESRD) on hemodialysis (HD): a single loading dose of 750 mg (500 mg and 250 mg) followed by a 150 mg (100 mg and 50 mg) maintenance dose administered intravenously every 8 hours for the remainder of the treatment period (on hemodialysis days, administer the dose at the earliest possible time following completion of dialysis)

We finalized in the CY 2022 PFS final rule (86 FR 65414) at 414.1365(c)(4)(ii) that an MVP Participant is scored on one population health measure in accordance with 414.1365(d)(1)

Dont rely on thirst as your only signal mild dehydration can be underway before thirst becomes noticeable, particularly once alcohol is already blunting some of your bodys normal signals

doi: 10.2174/1381612824666180614082950