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This damage not only contributes to the diseases initiation but also activates inflammatory signaling pathways, further amplifying the inflammatory cascade

At the same time, those affected with Crohns often undergo surgeries that involve the removal of at least a portion of the terminal ileum, placing them at further risk for a vitamin B12 deficiency

BMP5 contributes to hepcidin regulation and systemic iron homeostasis in mice

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[216] [217] Exactly how these results translate over to further biopsychological understanding of schizophrenia is still widely debated