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En los mtodos en el presente documento, tanto la forma zimgena de FX como la forma FXa o un fragmento catalticamente activo del mismo de cualquiera de los polipptidos de FX modificados proporcionados en el presente documento se pueden administrar a un sujeto

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Limitations of Use Because of the risks of addiction, abuse, misuse, overdose, and death, which can occur at any dosage or duration and persist over the course of therapy, reserve opioid analgesics, including acetaminophen and codeine phosphate tablets for use in patients for whom alternative treatment options are ineffective, not tolerated, or would be otherwise inadequate to provide sufficient management of pain