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PMC 5513687

Thus, we demonstrate that successful adaptation to the CNS microenvironment by ALL cells necessitates both lipid desaturation and successful LRP8-mediated organic selenium scavenging to provide adequate antioxidant defence in the context of extremely low thiol and cystine levels available from the CSF

Khattar S, Khan SA, Zaidi SAA, Darvishikolour M, Farooq U, Naseef PP, et al

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Individuals with cardiovascular risk factors such as hypertension, high cholesterol, or history of heart attack or bypass surgery are at increased risk of having an NSAID-related cardiovascular event (Conaghan 2012)