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Description

KYNA can confer protection against excitotoxicity via glutamatergic antagonism, yet excessive levels may simultaneously impair cholinergic signalling through 7nAChRs, contributing to mood and cognitive dysfunction

Gorovits, R

10.1016/0891-5849(92)90184-i Free Radic

The new research, which was conducted with Schistosoma maintained in laboratory conditions, shows that an oxadiazole compound was effective in inhibiting a crucial worm enzyme, called thioredoxin glutathione reductase (TGR)

Research has shown increased phosphorylation of extracellular signal-regulated kinases (ERK) 1 and 2, along with their downstream targets, including c-Fos, c-Jun, and Egr-1, which are molecules involved in cell growth, migration, and angiogenesis