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Recent studies showed that oxidative injuries were involved in neurodegeneration such as Alzheimers and Parkinsons disease [53,54], cancer [55,56], diabetes [57], and cardiovascular diseases [58,59]

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Similarly, the cysteine mutant (T399C) of BlGGT remained unprocessed, indicating the importance of the hydroxyl group in cleaving peptide bond (Lyu et al., 2009)

The fragment ion spectra of the S -mycothiolated Cys-peptides are characterized by diagnostic myoinositol-loss precursor ions (180 Da) that serve as markers for identification

Modulating p38 MAPK signaling by proteostasis mechanisms supports tissue integrity during growth and aging