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In vivo sensitisation of tumours by rhGH To extend and validate this study in vivo , we decided to use the anticancer drug daunorubicin, as TNF- , one of the main cytokines involved in sepsis (reviewed in Dinarello, 2000), may induce devastating effects after in vivo injection

The tail suspension test indicates that withdrawal from NEP increases the immobility time in mice, suggesting that drug withdrawal can trigger depression-like symptoms 46,47

Moreover, cancer cells can maintain a delicate balance of intracellular ROS levels