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The FDA is not bound by the committee's recommendation and may decline to add these compounds to the 503A bulks list

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In protein-calorie malnutrition, both GSH and CYP2E1 quantities would be reduced (as detailed by a reduction in both GSH and CYP2E1 messenger RNA) and thus there would be no net overall effect on toxicity [16, 85]

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Distinct Survival, Growth Lag, and rRNA Degradation Kinetics during Long-Term Starvation for Carbon or Phosphate