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Injectable routes carry a particular concern for immunogenicity from peptide aggregation and impurities, and FDA noted the available certificates of analysis for AOD-9604 bulk drug substances did not consistently control for impurities, aggregates, or microbial limits

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Yes, when prescribed and monitored by a qualified provider at therapeutic doses

Furthermore, Western blot results also indicated that the supernatant of tumor cells treated with NP4 promoted TRPM2 protein expression in macrophages (Fig