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Kovalzon, V

Sex differences and estradiol involvement in hyperalgesia and allodynia in an experimental model of fibromyalgia

Zhigancao decoction significantly reduced MMP-9 (matrix metalloproteinase-9) protein expression in AF rabbits and attenuated myocardial fibrosis, shortened field action potential duration ( CaL action period duration (APD) of rabbit atrial myocytes in the Zhigancao decoction group was significantly prolonged and the atrial ERP was prolonged too ( Dingji Fumai Decoction is a classic Chinese medicine compound with good anti-arrhythmic effect and high safety, but its effective components and specific mechanism of anti-atrial fibrillation are still unclear