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Funding This research was partially supported by AMED under Grant Number JP21mk0101197

Wrist circles, finger flexion and extension, and tendon gliding exercises maintain mobility without excessive strain on healing tissue

Because Dihexa lacked pharmaceutical-grade drug-like properties for clinical development, Athira Pharma instead developed fosgonimeton (ATH-1017), a phosphate prodrug that is rapidly converted to an active HGF/c-Met-potentiating metabolite following subcutaneous administration

Keywords: lesinurad, pharmacodynamics, pharmacokinetics, renal function, serum urate Introduction Gout is an inflammatory arthritis that results from high serum uric acid (sUA) levels, that is, hyperuricemia