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Description

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Yan H, Hao L, Chen H, Zhou X, Ji H, Zhou H

These exosomes effectively crossed the BBB, delivering BDNF directly to neurons in the hippocampus and prefrontal cortex

Not yet, and the gap is specific

Since oxidative stress is closely linked to DNA damage, the study also examined the extent of DNA lesions by quantifying H2AX, a marker of DNA double-strand breaks