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[0068] In some embodiments, the method comprises administering a composition comprising a cannabinoid, cofactor or precursor thereof, and antioxidant, wherein the cannabinoid is CBD, the cofactor or precursor thereof is niacinamide, and the antioxidant is L-ergothioneine

Malaguarnera and colleagues treating MHE patients with acetyl-L-carnitine (ALC) exhibited recovery of neuropsychological activities related to attention/concentration, visual scanning and tracking, psychomotor speed and mental flexibility, short-term memory, attention and computing ability, language, orientation ability and cognitive activities [59]

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Interestingly, it has recently been reported that the hydroxyl radicals originating from the Fenton reaction might not be the main product when a physiological concentration of bicarbonate is present in the system (Illes et al

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