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Iron accumulation-induced ROS, such as superoxide anion (O 2 -) and hydroxyl radical (OH), possess an unpaired electron at their outer orbit which allows them to react with all cellular components including proteins, lipids and nucleic acid

She has previously taught at the Birla Institute of Technology and Science (BITS), Pilani and the Central University of Andhra Pradesh, Anantapuram

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Therefore, additional methods with better specificity, such as myelin water fraction imaging (MWF) or ultrashort echo time (UTE)-magnetization transfer ratio (MTR)/FLAIR sequences 26,27,28 , could be used in subsequent studies for imaging myelin bilayer water molecules or myelin

And ethnic variations may play a role in genetic susceptibility