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Each of these functions has been shown in many contexts to be relevant for cancer pathogenesis

In: Male Hypogonadism: Basic, Clinical and Therapeutic Principles

In vivo studies further demonstrate that rhamnetin significantly reduces metastatic nodule formation in mouse models of lung and liver cancer [66]

1012 Although there was negligible overlap between p28 binding sites within the DBD of p53, p63, and presumably p73, p28 bound to p63 through hydrophobic interactions virtually identical to that with p53 (Figure 1B)