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Hydrogen peroxide produced by NADPH oxidases increases proline accumulation during salt or mannitol stress in Arabidopsis thaliana

Pemble, S., Ketterer, B

It is commonly applied in the treatment of advanced-stage cancers and chronic hepatitis B

While cellular senescence plays essential roles in tissue regeneration, tumor suppression, and embryonic development, the chronic accumulation of senescent cells due to processes such as aging, cellular stress, and other harmful agents contributes to the pathogenesis of age-related diseases, malignancies, metabolic diseases, and kidney diseases [5, 6]