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Assays were tested with 0 Gy, 15 Gy, and 15 Gy + 4 mM WR1065 to confirm usefulness for measuring radiation damage and radioprotection of individual SGm within the MB-hydrogel tissue chip (40-50 MBs per chip)

[DOI] [PubMed] [Google Scholar] 107.Maclean K.N., Jiang H., Phinney W.N., McLagan B.M., Roede J.R., Stabler S.P

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These include small molecule inhibitors that block the kinase activity of c-Met, monoclonal antibodies that neutralize HGF or inhibit its binding to c-Met, and multi-targeted inhibitors that disrupt both the HGF/c-Met and other RTK pathways