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Funding This work received support from the Consejo Nacional de Ciencia y Tecnologa (CONACYT) FOSEC SEP-INVESTIGACIN BSICA A1-S-26479, and the International Society for Neurochemistry-CATEGORY 1C: Return Home grant to AME-S

Samples were homogenized with a Bioruptor Next Gen (Diagenode) bath sonicator, set on HIGH and cooled to 4C, using 10 cycles of 10 s ON and 10 s OFF

After incubation for 1 h at room temperature, the incubated sample was analyzed

Studies (54,62,63) of the ChaC family have yielded conflicting findings regarding ChaC expression and its role in tumor tissues, emphasizing the complexity of GSH regulation and function