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Description

Pre-treatment with the AKT inhibitor MK2206 (4 M) significantly reduced glycolytic rates, particularly in AKT-E17K cells, pointing to AKT-dependent effects ( Figures 2CE )

Li, J., Chai, Q

ER stress is implicated in both the development of hepatic steatosis and the progression of NASH

Abbreviations: Hp: H

However, the comparative safety profile, particularly regarding critical adverse events like ILD, awaits direct clinical validation in ongoing and future studies