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Rational design of selective allosteric inhibitors of PHGDH and serine synthesis with anti-tumor activity

Each goal aligns with a different level of complexity and resource use, which is why pricing varies

Variability in outcome measures, ranging from angiographic to clinical vasospasm, and from DCI to functional outcomes, further complicates interpretation, as these endpoints differ in their sensitivity and specificity to vasospasm

Under obese conditions, LEPs regulatory effects on insulin sensitivity become attenuated, contributing to insulin resistance

[DOI] [PubMed] [Google Scholar] 9.Klein-Schwartz W, Doyon S