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Differential Diagnosis Considered etiologies included: Primary psychiatric disorder Neuroinflammatory or neurodegenerative disease Endocrine dysfunction Chronic infection (Lyme disease, EBV) Chronic inflammatory response syndrome (CIRS) Environmental toxin exposure (including mycotoxins) The acute onset, lack of psychiatric history, and environmental correlation made a primary psychiatric etiology less likely

Interestingly, we found that a large number of metabolic pathways became essential on the loss of FH, among which haem biosynthesis and degradation pathway and GSH biosynthesis were the most enriched

SURF1 mutant DNs exhibited reduced sodium and potassium currents compared to CTL DNs, lacked repetitive spiking and postsynaptic currents, and showed an increase in the number non-spiking neurons

Functional characterization of SLC39 family members ZIP5 and ZIP10 in overexpressing HEK293 cells reveals selective copper transport activity

Research demonstrates angiogenic signaling in vascular cell cultures