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Participants were randomly assigned to either one of three groups: placebo, 25 mg, or 50 mg of methylcobalamin, given twice a week, by injection into the muscle

Mysimba contains the active ingredients naltrexone and bupropion, which work by acting on the area of the brain that controls your appetite

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McElroy SL, Kotwal R, Hudson JI, Nelson EB, Keck PE

NICE Clinical Knowledge Summaries and British Society for Haematology guidelines support B12 supplementation in these clinical contexts, with treatment regimens tailored to the underlying cause