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& Guo, G

Among its toxic effects, oxidative stress appears to be the most critical, occurring primarily through two mechanisms: the generation of reactive oxygen species (ROS) and and the suppression of antioxidant defenses systems

Lundberg, M., Kawatsu, T., Vreven, T., Frisch, M

Reconstitution: 3.0 mL per 20 mg vial (~6.67 mg/mL) for accurate unit measurements on standard insulin syringes

However, as Voisenet already discovered in the early 20 th century 31,32 , 3-HPA spontaneously dehydrates to form acrolein, a cytotoxic electrophile 33,34 and a genotoxic mutagen 35