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Importantly the pressures generated by Froese and his team rather reflected gradients comparable to pressure induced by spontaneous breathing than high unphysiological gradients, emphasizing the role of spontaneous breathing as a relevant source of mechanical stress-released active TGF-1 (Hinz and Suki, 2016)

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Therefore, recognizing this chemical and functional distinction is not merely academic but imperative

The effect of selenium compounds on caspases, also known as cysteine-aspartic-specific proteases, includes the fragmentation of inter-nucleosomal DNA and the induction of the mitochondrial-dependent/independent apoptosis pathway [79]