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They're the leading cause of illness and death ( HTN is the primary cause of cardiovascular (CV) and kidney diseases, but diabetes mellitus (DM), smoking, and DL are also significant risk factors ( Metabolic syndrome (MS), characterized by a cluster of conditions like impaired glucose tolerance (GT), DL, obesity, and HTN, is a major risk factor for CVDs

Granulosa cells (both cumulus and granulosa cells) express high amounts of NAT and ASMT that help in the production of melatonin, and also receptors MT1 and MT2, which help in the binding of melatonin (185)

This makes it highly effective during cutting phases or body recomposition protocols

Typical oral dosages range 250500 mg daily for general antioxidant support, though bioavailability is limited

Combination protocols should always be guided by a qualified medical provider who can match the protocol to your lab work and goals